
Treatments
A single, non-surgical injection for knee osteoarthritis. Arthrosamid is a long-lasting hydrogel that eases joint pain and stiffness and can help delay, and in some cases avoid, a knee replacement, with relief shown to last for years.
about this treatment
Arthrosamid is a non-surgical treatment for knee osteoarthritis. It is an injectable hydrogel, made of around 97.5% sterile water and 2.5% polyacrylamide, given as a single injection into the knee joint under local anaesthetic.
Unlike steroid or hyaluronic acid injections, which wear off and often need repeating, Arthrosamid integrates into the lining of the joint and stays there. It makes the joint lining more cushioned and elastic, which reduces pain and stiffness and improves how the knee works. The full benefit builds gradually over around six to twelve weeks, and most suitable patients experience meaningful relief.
It is important to be clear that Arthrosamid does not cure osteoarthritis or stop it progressing. What it can do is provide lasting relief, with studies showing benefit maintained at three to five years. It can help you delay, and in some cases avoid a knee replacement. Mr Oni will assess your knee and advise whether Arthrosamid is the right option for you.

is this right for me?
Arthrosamid suits people with knee osteoarthritis who want a non-surgical option, particularly when other measures have stopped helping or when a knee replacement is not yet wanted or appropriate.

Ongoing knee pain and stiffness from osteoarthritis, confirmed by Mr Oni on examination and imaging.

Physiotherapy, weight management, pain relief, or steroid and hyaluronic acid injections have stopped helping or do not last.

Not ready for, or not yet suitable for, a knee replacement and looking for lasting relief in the meantime.
Not sure if you qualify?
Many patients come to Mr Oni uncertain whether their symptoms are "bad enough" for treatment. The answer always comes from a proper clinical assessment - not from a website. Book a consultation and Mr Oni will give you an honest view.
outcomes
the benefits and outcomes that are typically expected with this treatment. giving you realistic expectations are important to ensure you go into any treatment fully informed.
A simple injection under local anaesthetic, with no surgery, no general anaesthetic and no hospital stay.
Unlike steroid or hyaluronic acid injections, a single Arthrosamid injection integrates with the joint and has been shown to keep working at five years.
One injection rather than a repeated course, with most people back to normal activities the same day.
For the right patient, Arthrosamid can give lasting pain relief and help delay or avoid a knee replacement.
There is no surgical recovery with Arthrosamid. Most people return to normal activities soon afterwards, while the full benefit builds gradually over the following weeks.
Some mild pain, stiffness or swelling is normal and usually settles within a few days. Rest and ice the knee as needed.
You can return to normal daily activity while the hydrogel integrates with the lining of the joint.
Pain and stiffness steadily improve as the hydrogel becomes fully integrated and starts working at its best.
Relief is long-lasting, with clinical studies showing benefit maintained at three to five years after a single injection.
Arthrosamid is designed to be long-lasting. Clinical studies show benefit maintained at three to five years after a single injection, although individual responses vary.
Steroid and hyaluronic acid injections are temporary and often need repeating. Arthrosamid is a single injection that integrates into the lining of the joint, which is why its relief tends to last far longer.
No. Arthrosamid does not cure osteoarthritis or stop it progressing, but it can give meaningful relief from pain and stiffness and help you delay and in some cases, avoid a knee replacement.
The cost depends on whether one or both knees are treated and whether you are self-funding or using private medical insurance. Mr Oni's team can provide a clear quote at your consultation.
It is a single injection into the knee under local anaesthetic, taking only a few minutes as an outpatient. You are given antibiotics beforehand and go home the same day, with some mild soreness possible for a few days.
Arthrosamid is not used where there is an active knee infection, and where arthritis is very advanced a knee replacement may be a better option. Mr Oni will advise whether it is right for you.
Mr Oni consults and operates at several leading private hospitals across the region, so you can choose the location most convenient for you.
get in touch
See Mr Oni at The Horder Centre, The Nuffield Hospital or The Vale Health Clinic.
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We accept most major UK private medical insurers, and welcome self-funding patients too.






